MyBioSource.com's PEZ antibody is a Mouse monoclonal antibody. The PEZ antibody was generated using PTPN14 as the antigen. It reacts with Human, and Drosophila/Arthropod. This antibody has been shown to work in applications such as: Western Blot.
Description
Mouse monoclonal PEZ antibody
PEZ is a 130 kDa multidomain cytosolic protein, and belongs to the NT6 subtype of PTPs. It is characterized by an N-terminal FERM domain (Band 4.1, ezrin, radixin, moesin homology) and a C-terminal PTP domain. Pez (Phosphatase with ezrin domain) may play a role in regulating endothelial cell proliferation during vascular injury and angiogenesis. B-Catenin, a central component of adherens junctions, has been identified as a PTPN14 substrate. TGF, which inhibits cell proliferation but not migration, also inhibits translocation of PTPN14 from the cytosol to the nucleus